Regeneron is founded in 1988, and in 1992 began the clinical trial a neurotrophic factor. However, in 1997 the Phase 3 in the clinical trial didn't achieve its primary endpoint but they didn't give up and decided to focus on new therapeutic solutions. Regeneron pharmaceuticals collaborated with other companies such as Bayer HealthCare and Sanofi to develop fully human antibodies. They begin sponsorship of a mobile laboratory, named BioBus which contributes to science education in underserved school districts In 2013 they opened their European business office in Dublin, Ireland. E 2015 Regeneron started operations in Limerick, being considered the largest bioprocessing campus in Ireland. Where manufactures a broad range of biopharmaceuticals for patients. Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for high LDL cholesterol, eye diseases.