Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Let’s do this. Let’s change the world. In this vital role you will join the Drug Substance Technologies – Synthetics (DSTS) group within Process Development at our Cambridge, Massachusetts site.

The DSTS organization is responsible for the invention, development, and implementation of innovative drug substance manufacturing processes and technologies that advance Amgen’s growing portfolio of small molecule and hybrid therapeutics. Our process chemists leverage deep expertise in organic chemistry to design efficient synthetic routes and scalable chemical processes that support drug substance manufacturing from early through late-stage development.

The successful candidate will be a collaborative, scientifically driven individual with strong expertise in organic chemistry, a passion for innovation, and a demonstrated record of scientific achievement.

Responsibilities:

• Design and develop synthetic routes and scalable chemical processes for the manufacture of synthetic and hybrid drug substances
• Develop safe, robust, efficient, and cost-effective manufacturing processes suitable for clinical and commercial production
• Advance enabling technologies that accelerate pharmaceutical development and improve sustainability, efficiency, and process robustness
• Support cGMP manufacturing activities and assist with technology transfer efforts to internal manufacturing sites and external contract manufacturing organizations (CMOs)
• Build process understanding through experimentation, process characterization, modeling, and data analysis to ensure consistent process performance
• Contribute to cross-functional drug substance development teams by providing technical expertise, experimental data, scientific recommendations, and clear documentation
• Collaborate across disciplines to support regulatory filings and author technical sections of regulatory documentation
• Stay current with advances in synthetic organic chemistry, process chemistry, and related technologies, and apply new scientific insights to ongoing programs
• Effectively collaborate within multidisciplinary teams that include chemists, engineers, analytical scientists, and other technical experts
• Independently manage project activities and deliver high-quality results within established timelines

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Scientific professional we seek is an individual with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] completed by August 2026
OR
Master’s degree and 3 years of Scientific experience
OR
Bachelor’s degree and 5 years of Scientific experience

Preferred Qualifications:

• Ph.D. in Organic Chemistry with expertise in total synthesis, reaction methodology, mechanistic chemistry, and/or process development
• Postdoctoral experience in academia or the pharmaceutical/biotechnology industry
• Experience with ADC, peptides
• Demonstrated track record of scientific innovation through peer-reviewed publications, patents, and/or conference presentations
• Strong problem-solving skills and ability to work effectively in a dynamic, interdisciplinary research environment
• Excellent written and verbal communication skills, with strong organizational and time management abilities
• Ability to manage multiple priorities and drive complex projects to completion
• A research summary submitted with the CV is strongly encouraged

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.