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A one-month antibiotic regimen to prevent active tuberculosis (TB) disease was at least as safe and effective as the standard nine-month therapy for people living with HIV, according to the results of a large international clinical trial. Adults and adolescents in the trial were more likely to complete the short-course regimen — consisting of daily doses of the antibiotics rifapentine and isoniazid for four weeks—than the standard nine-month regimen of daily isoniazid. http://glassdoor.com/slink.htm?key=vQj9M
National Institutes of Health (NIH) scientists developing a rapid, practical test for the early diagnosis of prion diseases have modified the test to offer the possibility of improving early diagnosis of Parkinson’s disease and dementia with Lewy bodies. http://glassdoor.com/slink.htm?key=vQN3C
The Center for Translational Research and Implementation Science (CTRIS) is seeking an exceptional and motivated physician to serve as a medical officer within the Implementation Science Branch (ISB). ISB supports basic, clinical, and translational research on the prevention and treatment of heart, lung, blood, and sleep disorders, through implementation research for populations and communities in real-world settings. The medical officer will have a wide range of responsibilities relating to the oversight of extramural clinical research programs. Duties include the development of implementation research concepts, oversight of clinical protocols, scientific reviews, and engagement with researchers, stakeholders, and the public. Learn more and apply here: http://glassdoor.com/slink.htm?key=vQNrk
Researchers found that certain biological differences didn’t predict whether someone would lose more weight from a low-fat or low-carbohydrate diet. People lost weight on both diets, which emphasized choosing healthy food options rather than counting calories. Read more http://glassdoor.com/slink.htm?key=vQN1m
National Institute of Allergy and Infectious Diseases (NIAID) scientists have demonstrated that slight changes to a powerful, naturally occurring HIV antibody help it last longer in the human body while counteracting the virus just as well in the laboratory. These characteristics could reduce the cost and increase the convenience of giving people antibodies for HIV prevention because fewer doses of an antibody may achieve the same protective effect. http://glassdoor.com/slink.htm?key=vQNs8
When a life-threatening storm is bearing down, most people wouldn't think of the NIH Clinical Center. But employees who work in the hospital were among the many responders helping Americans devastated by hurricanes in 2017. http://glassdoor.com/slink.htm?key=vQNRs
Want to help researchers learn more about why people get sick or stay healthy? Share your ideas to make the @AllofUsResearch Program the best resource it can be. Learn more & submit your ideas by Feb. 23: http://glassdoor.com/slink.htm?key=vQNXq #PrecisionMedicine #JoinAllofUs
The brains of humans and other mammals have the potential to produce new neurons throughout life thanks to a specific type of cell—adult neural stem cells. A recent NIH Director's Blog tells us more about research on these cells! http://glassdoor.com/slink.htm?key=vQNAh
A research team developed a way to stimulate immune cells to attack cancer cells in the body. They identified two compounds that could be injected into mice and work together to stimulate immune cells. After the compounds were injected directly into a tumor, the immune cells killed that tumor and distant tumors of the same type. Find the story at http://glassdoor.com/slink.htm?key=vQ7UM
NIH-funded researchers identify risk factors for sleep apnea during pregnancy Snoring, older age and obesity may increase a pregnant woman’s risk for sleep apnea — or interrupted breathing during sleep — according to researchers funded by the National Institutes of Health. The study, which appears in the American Journal of Obstetrics and Gynecology, was supported by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National Heart, Lung, and Blood Institute. “Our study found an easy, inexpensive way to screen large numbers of women at higher risk of sleep apnea during pregnancy,” said study co-author Uma Reddy, M.D., of NICHD’s Pregnancy and Perinatology Branch. “Right now, this means we’ll be able to rapidly identify women who may benefit from further testing. Depending on what we learn from future studies, our findings could also lead to improvements in pregnancy outcomes.” Read more here: http://glassdoor.com/slink.htm?key=vQ7g5
